Overview
Pepnova Sermorelin is a research-grade analog of Growth Hormone-Releasing Hormone (GHRH 1-29), comprising the biologically active N-terminal segment. This peptide serves as a precise tool for studying the natural, pulsatile stimulation of endogenous growth hormone (GH) secretion from the pituitary gland, mimicking the body’s own signaling mechanism.
Key Features & Benefits
- Natural GH Release Profile: As a GHRH analog, it stimulates the pituitary to release growth hormone in a pulsatile manner, closely replicating the body’s physiological pattern for research purposes.
- Focused Receptor Interaction: Binds selectively to the GHRH receptor on pituitary somatotrophs, providing a specific research model for studying this signaling pathway without direct GH injection.
- Shorter Half-Life for Pulsatility Studies: Its relatively short half-life makes it ideal for research protocols designed to study episodic GH pulses and their distinct metabolic effects.
- High-Purity & Reliable: Synthesized as a 29-amino acid peptide to ≥ 99% purity (HPLC verified), ensuring consistent and accurate research outcomes.
Primary Research Applications
- Study of pulsatile growth hormone secretion and its downstream effects on metabolism and body composition.
- Research into age-related decline of GH secretion and potential interventional models.
- Investigation of the GHRH receptor pathway and pituitary somatotroph function.
- Used as a comparator to other GH secretagogues (like Ipamorelin) to contrast receptor mechanisms.
Product Specifications
- Unit Size: 10mg
- Compound: Sermorelin (GHRH 1-29)
- Purity: ≥ 99% (HPLC verified)
- Sequence: 29-amino acid peptide (Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2)
- Form: Lyophilized (freeze-dried) powder
- Molecular Weight: ~3.4 kDa
- Storage: Store in a cool, dry place. For long-term stability, refrigeration is recommended.
Important Notice
This product is for chemical and laboratory research purposes only. It is not for human or veterinary consumption, diagnosis, or treatment. Sermorelin is a potent peptide and should be handled by qualified researchers in a controlled laboratory setting.




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