Overview
Pepnova SS-31 (Elamipretide) is a groundbreaking, cell-permeable mitochondrial-targeting peptide designed for advanced research into cellular energy, oxidative stress, and age-related dysfunction. This innovative tetrapeptide selectively concentrates in the inner mitochondrial membrane, making it a powerful tool for studying mitochondrial integrity, bioenergetics, and cytoprotection.
Key Features & Benefits
- Mitochondria-Specific Targeting: Engineered with a unique alternating aromatic-cationic structure that enables it to cross cell membranes and accumulate several hundred-fold within the inner mitochondrial membrane, allowing precise organelle-level research.
- Potent Antioxidant & Membrane Stabilizer: Binds to cardiolipin, a key phospholipid in the inner mitochondrial membrane, helping to research protection against oxidative damage and maintenance of cristae structure for efficient ATP production.
- Enhances Cellular Bioenergetics: Facilitates studies on improving mitochondrial efficiency, ATP synthesis, and reducing electron leak, which is central to research on aging, metabolic disorders, and neurodegeneration.
- High-Purity Research Grade: Synthesized to ≥ 99% purity (HPLC verified) with the D-arginine isomer configuration essential for its stability and bioactivity, ensuring reliable experimental outcomes.
Primary Research Applications
- Research into mitochondrial dysfunction in aging, neurodegeneration, and metabolic diseases.
- Study of oxidative stress reduction and protection against reactive oxygen species (ROS) within mitochondria.
- Investigation of cellular bioenergetics, ATP production, and metabolic efficiency.
- Models of ischemia-reperfusion injury, cardiovascular disease, and other conditions linked to mitochondrial failure.
Product Specifications
- Unit Size: 50mg
- Compound: SS-31 (Elamipretide, Bendavia)
- Purity: ≥ 99% (HPLC verified)
- Sequence: D-Arg-Dmt-Lys-Phe-NH2 (where Dmt = 2′,6′-dimethyltyrosine)
- Form: Lyophilized (freeze-dried) powder
- Molecular Weight: ~639.8 Da
- Storage: For maximum stability of this sensitive peptide, store desiccated at or below -20°C. Protect from light and moisture.
Important Notice
This product is for research and laboratory use only. It is not for human or veterinary consumption, nor is it a drug or supplement. SS-31 is a potent, targeted peptide for mitochondrial research and must be handled by qualified professionals using appropriate laboratory safety procedures.





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